We studied the demographic characteristics and health-related quality of life (HRQOL) in diabetics with skin ulcers.
We also compared treatment with Lipo PGE
1 (Liple
®) before and after with clinical features estimated by a physician and with the HRQOL, which has attracted international attention as a method of evaluating medical care.
We used SF-36, the most widely used instrument in 134 facilities in Japan, from September 1999 to October 2001.
To avoid bias in selection, patients were registered by fax to the entry center before treatment with Lipo PGE, .
In the before-and after-comparison, unpaired Student's t-test, the Wilcoxon one-sample test, etc., were used for statistical comparision.
Five of 8 subscales of SF-36 used to assess patients, including those hospitalized, were significantly lower compared to norms for a representative sample of the Japanese population.After treatment including LipoPGE
1, these significantly improved clinically features as evaluated by a physician.The physical HRQOL score for patients, however, did not show an improved mental score.
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