A 60-year-old woman diagnosed with insulin-dependent diabetes mellitus at age 31 and treated with insulin since then was diagnosed with bilateral sensory deafness of unknown origin when 33 years old.Mitochondrial 3243 A-G point mutation was detected when she was 51 years old.Because of worsening glycemic control, she was admitted at age 60.She had no evidence of diabetic microangiopathy regardless of a 30-year disease duration.
In general, MIDD is thought to be associated with a high prevalence of microangiopathy.We report this case because of its importance in recognizing that some cases do not exhibit microangiopathy regardless of long disease duration in clinical practice and in understanding the mechanisms of diabetic microangiopathy development.