Previously, we reported that irradiation by waves from EQR (emission from quartz resonance) had a strong tendency to suppress proliferation of sarcoma 180 tumor cells in BDF1 mice, and to markedly inhibit carrageenin-mduced foot edema in rats. In the present investigation, influence of EQR irradiation on animal rectal temperature was examined. We found that EQR irradiation increased the rectal temperature. The amount of the temperature increase gradually decreased during repetition of the irradiation even in a time interval (30 min) shorter than that (several days) in the former report. We postulated that the effect arose because the EQR waves affected the autonomic nerve system.