DPX-F5384, methyl 2-[[[[[(4, 6-dimethox-pyrimidin-2-yl) amino] carbonyl] amino] sulfonyl]methyl]benzoate and several analogs were examined for herbicidal activities, crop safety, and selectivity.
(1) Both DPX-F5384 and DPX-T6375 which have substitutents of 2-CO
2CH
3 were tested in petri dishes to examine their effect during early growth stage of rice,
Brassica pekinensis and
Sagittaria pygmaea. The results indicated that DPX-F5384 has the highest selectivity between rice and other plants. DPX-T6357 provided little selectivity.
(2) DPX-F5384 and the analogs were tested for herbicidal activity and crop safety under paddy rice conditions. DPX-W4515, DPX-T6375, DPX-W4189, and DPX-T6376, all with phenyl moiety, exhibited very high weed control activity, but caused severe phytotoxicity on transplanted rice exhibiting little selectivity between rice and weeds. DPX-F5384, with 2-CO
2CH
3 substituted benzyl moiety, was highly active, 2-Cl substituted DPX-F5390 had very low activity. In contrast to the benzyl type derivatives, DPX-R5582, with 2-Cl substituted phenoxy, had considerably high activity.
Among the sulfonylurea compounds exa mined, DPX-F5384 proved to have sufficient crop safety for rice. DPX-R5582 was relatively safe to rice but its safety margin was not broad enough. In addition, DPX-R5582 was not particularly active on
Scirpus juncoides, one of the major weeds in rice paddies. DPX-F5384 was the best compound based on its high weed control activity and selective safety to rice.
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