肥満を伴う2型糖尿病患者における減量治療法の新しい試み

榎澤 尚子; 井上 穣; 佐藤 勉; 大塚 史子; 青木 兼実; 高橋 育克; 高橋 隆; 佐藤 尚太郎; 升田 雄史; 谷山 松雄; 鈴木 晟時

doi:10.11213/tonyobyo1958.47.635

New Trial in Diet Therapy for Weight Reduction in Obese Type 2 Diabetic Patients

Naoko Enosawa, Minoru Inoue, Tsutomu Sato, Fumiko Otsuka, Kanemi Aoki, Yasuyoshi Takahashi, Ryu Takahashi, Shotaro Sato, Yuji Masuda, Matsuo Taniyama, Seiji Suzuki

Author information

Naoko Enosawa
Division of Endocrinology and Metabolism, Department of Internal Medicine, Showa University Fujigaoka Hospital
Minoru Inoue
Division of Endocrinology and Metabolism, Department of Internal Medicine, Showa University Fujigaoka Hospital
Tsutomu Sato
Division of Endocrinology and Metabolism, Department of Internal Medicine, Showa University Fujigaoka Hospital
Fumiko Otsuka
Division of Endocrinology and Metabolism, Department of Internal Medicine, Showa University Fujigaoka Hospital
Kanemi Aoki
Division of Endocrinology and Metabolism, Department of Internal Medicine, Showa University Fujigaoka Hospital
Yasuyoshi Takahashi
Division of Endocrinology and Metabolism, Department of Internal Medicine, Showa University Fujigaoka Hospital
Ryu Takahashi
Division of Endocrinology and Metabolism, Department of Internal Medicine, Showa University Fujigaoka Hospital
Shotaro Sato
Division of Endocrinology and Metabolism, Department of Internal Medicine, Showa University Fujigaoka Hospital
Yuji Masuda
Division of Endocrinology and Metabolism, Department of Internal Medicine, Showa University Fujigaoka Hospital
Matsuo Taniyama
Division of Endocrinology and Metabolism, Department of Internal Medicine, Showa University Fujigaoka Hospital
Seiji Suzuki
Division of Endocrinology and Metabolism, Department of Internal Medicine, Showa University Fujigaoka Hospital

JOURNAL FREE ACCESS

2004 Volume 47 Issue 8 Pages 635-641

DOI https://doi.org/10.11213/tonyobyo1958.47.635

Details

Abstract

In diet therapy for weight reduction in obesity, an issue is adaptive phenomenon (AP) in which weight loss stops. We evaluated avoiding such AP in obese type 2 diabetic patients. Patients who could be admitted for 8 weeks were put on low calorie diets (LCDs) of 1, 000 kcal/day for men and 800kcal/day for women. To avoid AP, LCDs were switched to standard diets (35kcal/kg standard body weight) for 1 week, then LCDs were started again (Group A, n=15). As a control for the age-matched group, LCDs were continued for 8 weeks despite AP (Group B, n=14). In Group A, all patients avoid AP and continued to lose weight. At 8 weeks after the start of treatment, 12.3±2.5% weight loss was noted. In Group B, the rate of decrease in body weight was 8.8±2.7%. Our method in which energy intake was increased for a short period followed by a return to LCDs was useful for avoiding AP and enhancing weight loss during the same period.

Corresponding author

Register with J-STAGE for free!