Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
Online ISSN : 1882-5133
Print ISSN : 1345-2843
ISSN-L : 1345-2843
A CASE OF ADVANCED GASTRIC CANCER WITH MULTIPLE LIVER METASTASES SUCCESSFULLY TREATED WITH POST OPERATIVE INTRAHEPATIC CHEMOTHERAPY AND ORAL ADMINISTRATION OF 5'-DEOXY-5-FLUOROURIDINE
Hiroshi NAKASHIMAYoshihiko HAYASHIKouichi FURUGAKIHidekazu NISHINAKATakahito KASHIWAGI
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2000 Volume 61 Issue 10 Pages 2647-2651

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Abstract
A 73-year-old man was seen at the hospital because of slight fever. Gastric endoscopy revealed a type I elevated lesion in the anterior wall of the middle to upper porrtions of the gastric body. Biopsy indicated well differenciated adenocarcinoma. Abdominal CT scan revealed multiple metastatic lesions in the both lobes of the liver. To relieve hemorrhage from the primary foci and passage disturbance, a subtotal gastrectomy (D1+#8) and hepatic artery cannulation were performed. We treated the liver metastases with hepatic arterial infusion of Cisplatin (10mg) and 5-fluorouridine (250mg) and oral administration of 5'-deoxy-5-fluorouridine (5'-DFUR, 600mg). After treated with this regimen for 2 Kurs, the liver metastases disappeared completely on computed tomography. He had been well with no evidence of recurrence for 16 months after the operation by only oral administration of 5'-DFUR.
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