Neurological Therapeutics
Online ISSN : 2189-7824
Print ISSN : 0916-8443
ISSN-L : 2189-7824
 
Usefulness of serial gait function evaluations in Parkinson's disease patients who underwent unilateral magnetic resonance imaging–guided focused ultrasound thalamotomy : A report of two cases
Kazutaka HorikoshiHisashi ItoAyuko YamazakiShigeru FukutakeKazuaki YamamotoHiroki WatanabeTetsumasa Kamei
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2018 Volume 35 Issue 5 Pages 633-636

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Abstract

We report two cases in which patients with Parkinson's disease underwent unilateral magnetic resonance imaging–guided focused ultrasound (MRgFUS) thalamotomy for medication–refractory tremors. Both patients were males in their 70s, and their resting tremors disappeared immediately during the procedure ; however, severe bradykinesia and gait disturbance persisted. The administration of corticosteroids for severe edema around the targeted lesions ameliorated the bradykinesia and gait disturbance. In addition to the Unified Parkinson's Disease Rating Scale, serial examinations of gait function, including the timed up & go test and the comfortable gait speed in 10–m walking test, were useful for evaluating the patients' motor functions.

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© 2018 Japanese Society of Neurological Therapeutics
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