Abstract
A 68-year old man was examined using arthrography, without any apparent complications. However, approximately 12 hours later, the patient went into a state of shock, which we suspected was caused by the contrast media. He was transferred to the ICU, where his blood pressure was found to be 40/20mmHg and his heart rate was 130min-1. In the ICU, we immediately started fluid therapy and administered catecholamines and steroids. Examination also revealed a decrease in blood platelets and an increase of fibrin degradation product (FDP), and disseminated intravascular coagulation (DIC) was diagnosed. In addition, the patient's liver enzyme levels were elevated and impaired renal function was noted. Anticoagulation therapy and continuous hemodiafiltration (CHDF) were started because of the DIC and renal dysfunction, after which the patient's circulatory condition gradually stabilized. The general condition of the patient improved after 22 days and he was then discharged from the ICU. In vitro lymphocyte stimulation test turned to be positive to the contrast media, Conray. The side effects of arthrography are rare and few reports are available regarding delayed shock caused by the contrast media. Furthermore, this case is unusual, because the shock was delayed until at least 12 hours after the arthrography examination. We concluded that the patients should be carefully monitored for the delayed severe reaction to the contrast media following arthrography.