Journal of Animal Clinical Medicine
Online ISSN : 1881-1574
Print ISSN : 1344-6991
ISSN-L : 1344-6991
Case Report
Detection of Marginal Zone Lymphoma with a Remarkable Increase in Peripheral Blood Lymphocytes in a Dog
Mai ASANO, Yuki SHOJI, Takuya KANDA, Ai KISHIDA, Kohei KISHIDA, Satoshi MATSUURA, Atsushi HASHIMOTO, Mako OTSUKA, Akina MIYAMOTO, Tetsuya SHIMODA, Yuji FUJII
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Keywords: canine, MZL, low grade lymphoma
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2020 Volume 29 Issue 4 Pages 162-166

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Abstract

A 9-year-old male Chihuahua was referred to our hospital for lymphocytosis. There was a marked increase in small to middle-sized lymphocytes in the peripheral blood smear and cytology of the spleen. Clonal analysis of lymphocytes using peripheral blood showed clonal expansion of B cells. Bone marrow examination confirmed an increase in small lymphocytes that accounted for more than 50% of all nucleated bone marrow cells. Chronic lymphocytic leukemia was suspected based on the above results; however, histopathological evaluation of the spleen revealed marginal zone lymphoma.

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© 2020 Japanese Society of Clinical Veterinary Medicin
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