Press-through packages (PTPs) are widely used to enclose drugs. A number of studies have reported gastrointestinal foreign body and gastrointestinal perforation caused by accidental ingestion of PTPs. An 81-year-old woman presented to our emergency department with a complaint of abdominal pain. Her family was worried that she might have inadvertently swallowed tablets that were still in the PTP. Abdominal computed tomography (CT) revealed intraabdominal free air and detected a high-density object in the small intestine; this suggested the presence of a tablet. Moreover, CT revealed a high-density opacity in the stomach, which was suspected to be a PTP. A diagnosis of perforation of the small intestine and presence of foreign body in the stomach caused by accidental ingestion of two PTPs was established; emergency surgery was performed on the same day. On laparotomy, a perforation caused by PTP was found in the small intestine. The PTP was removed and the perforated portion of the small intestine was surgically restored. Subsequently, the PTP in the stomach was endoscopically removed without complications. There have been few reports on gastrointestinal perforation due to multiple PTPs in the digestive tract. We suggest that in patients with gastrointestinal perforation caused by PTPs, the possibility of presence of multiple PTPs be considered to make a correct diagnosis and determine the appropriate treatment approach.
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