The aim of this study was to investigate the relationships between oxidative stress, dietary habits and quality of life (QOL) in middle-aged and elderly women. In 26 women aged 40 years or more, we investigated age, body mass index (BMI), blood pressure, oxidative stress level (d-ROMs test), antioxidant power (BAP test), modified ratio of oxidative stress to antioxidant power (BAP/d-ROMs/7.541; relative tolerance to oxidative stress), total cholesterol, LDL cholesterol, HDL cholesterol, dietary intake, blood vitamin C and E levels, and health-related QOL (as determined by the SF36).
There were no significant differences in the degree of oxidative stress between reproductive function levels. Multiple logistic regression analysis revealed a significant factor: BMI in BAP level (OR=0.55, CI=0.25-0.91) and relative tolerance to oxidative stress (OR=2.31, CI=1.03-9.55). Although there were no significant differences between BAP level and vitamin C level with differences in dietary intake, there was a positive correlation between BAP level and blood vitamin C level (r
s=0.40, P=0.046). In terms of QOL, there was a positive correlation between physical component summary score and BAP level (r
s=0.47, P=0.017), or relative tolerance to oxidative stress (r
s=0.59, P=0.001). These results suggest that, in middle-aged and elderly women, increased BMI is related to oxidative stress, and BAP levels are increased by vitamin C. As a result, physical QOL may improve.
View full abstract