We experienced a case of carcinoma arising in the reconstructed gastric tube after a radical operation for esophageal cancer. This patient, a 73-year-old man who had undergone haemodialysis for 10 years due to chronic renal failure, underwent subtotal esophagectomy and retrosternal reconstruction by a gastric tube for esophageal cancer 3years earlier. Ⅱc type early cancer of the gastric tube was discovered in the middle part of the stomach by periodic endoscopy in September 2012. Endoscopic biopy showed signet ring cell carcinoma so endoscopic mucosal resection was unable to be indicated for the case. The patient rejected the operation of a resection of the gastric tube, and he was therefore adminis-tered oral UFT. We followed this case by gastroendoscopy every three months and by PET/CT every six months. PET in May 2013 demonstrated metastases of right bronchopulmonary lymph nodes, so we administered only 2 course of CPT-11（bi-weekly drip infusion）added to oral UFT. As of 2 years after the administration of UFT, the patient is still doing well. In July 2014, endoscopy revealed reduction of the Ⅱc lesion and pathological findings of a specimen revealed no residual cancer cells, indicating a partial response to UFT therapy. The prognosis of cancer in the gastric tube is generally poor, but many suvivors have been reported due to early diagnosis. Regular endoscopy every 6 monthes after esophagectomy is necessary to detect the disease in an early stage. Oral uracil and tegafur therapy is considered to be one of treatment option for the patients with early cancer of gastric tube from a standpoint of clinical efficacy and safety.