Concerning the studies of life’s origin, there has been a serious dilemma or a chicken-and-egg paradox how does evolution starts out of randomly reacting chemical soup. Actually, evolving units such as self-replicating polymers could not arise without evolving processes, whereas evolving processes would not begin without evolving units. The processes of life’s origin and its evolution can be considered as the continuous complexation of initially nonliving entities leading to highly complex living organisms. A concept of self-replicating polymers alone can not attack the above-mentioned dilemma, because it can not link different levels of the hierarchy and hence no complexation appears. The present paper assumes that self-replicating units may not be the cause of life’s origin, but instead it may be the result emerging from quite different dynamical processes. It is a new paradigm of ‘endo-exo (or self-nonself) circulation’ that was introduced to account for such dynamical processes.