Life was generated about four billion years ago in the primitive sea as a result of the chemical evolution. The proto-cell was a prokaryotic monad that was formed from a certain aggregate of primitive proteins, nucleic acids, and other macromolecules and wrapped with (phospho)lipid membrane. That membrane served a very important role in the proto-cell born in the primitive sea. This communication addresses the evolutionary process of eukaryotic cell genesis. Eukaryotic cells developed membrane systems remarkably compared to prokaryotic cells. The nucleus, mitochondria, chloroplasts (in plant), endoplasmic reticulum, Golgi apparatus, and other organelles are constructed of lipid membranes inside of which specific enzymes and proteins are positioned. We infer that the eukaryotic organelles were not engendered in an accidental event of symbiotic phenomena, but by evolutionary inevitability of the surviving world.