A 58-year-old man with a 12-year history of poorly controlled diabetes mellitus admitted in October 1999 for left buttock pain and swelling had had multiple skin ulcers around the bilateral ankle joints for over 5 years. Methicillin-resistant Staphylococus aureus (MRSA) had been detected from the ulcer exudate. On admission, his leucocyte count was 16, 700/μl and serum C-reactive protein (CRP) 24.6mg/dl. Computed tomography (CT) showed multiple low-density areas in the left gluteus maximus muscle. We diagnosed gluteal abscesses and conducted surgical drainage. MRSA was cultured from a sample of pus from the left gluteal abscess, exudates from the right ankle, venous blood, and urine. Surgical drainage, antibiotic therapy, and strict glycemic control with combined to provide marked clinicalimprovement. We concluded that MRSA bacteremia caused abscesses in the left gluteus maximus muscle. Because diabetics are at risk for potentially adverse reactions to immunization, strict glycemic control is important.