外科的切除後，血清chromogranin A濃度が上昇したインスリノーマの1例

中野 温子; 竹田 章彦; 髙田 絵美; 纐纈 優子; 木股 邦恵; 川口 晴菜; 門澤 秀一; 小松原 隆司; 藤本 康二; 市川 一仁; 藤盛 孝博

doi:10.11213/tonyobyo.61.15

Case Reports

A Case of Insulinoma in Which Serum Chromogranin A Increased After Its Surgical Resection

Atsuko Nakano, Akihiko Takeda, Emi Takata, Yuko Koketsu, Kunie Kimata, Haruna Kawaguchi, Syuichi Monzawa, Takashi Komatsubara, Koji Fujimoto, Kazuhito Ichikawa, Takahiro Fujimori

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JOURNAL FREE ACCESS

2018 Volume 61 Issue 1 Pages 15-21

DOI https://doi.org/10.11213/tonyobyo.61.15

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Abstract

A 29-year-old woman was admitted to our hospital due to unconsciousness. She was diagnosed with insulinoma, and distal pancreatectomy was performed. However, her serum chromogranin A (CgA) levels increased after surgery. We therefore examined the patient for metastasis and recurrent insulinoma; but they were not detected. According to previous reports, the serum CgA level in the serum is useful as a diagnostic and follow-up biomarker in cases involving neuroendocrine tumors other than insulinoma. It is more important for clinicians to ask patients about hypoglycemic symptoms and to perform imaging studies when recurrence or metastasis of insulinoma is suspected.

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