Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
Online ISSN : 1882-5133
Print ISSN : 1345-2843
ISSN-L : 1345-2843
A CASE OF GOBLET CELL CARCINOID OF THE APPENDIX REVEALED POSITIVE STAINING WITH CYTOKERATIN ANTIBODY NO.20
Hiroshi NEMOTOYasuo YOSHIZAWAKunitoshi AITAShoji SASAYATakemasa MIDORIKAWAYutaka SANADAGenshu TATE
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2005 Volume 66 Issue 7 Pages 1665-1669

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Abstract
An ileocecal mass was detected in a 73-year-old woman who was admitted for close examination to lower abdominal pain, generalized edema, and positive signs of inflammation. Perforation of the digestive tract occurred during hospital stay, and an ileocecal resection was immediately carried out. On the resected material, the ilocecal region was hard and thickening and a round ulcer with perforation was noted on the oral side of the ileum. Tumor cells were detected from the distal end of the ileum toward the appendix, and invasion to the ileum of primary goblet cell carcinoid of the appendix was diagnosed. On cytokeratin staining, the tumor was CK20 positive that is a specific pattern of colon cancer. The results of cytokeratin staining in this case are of interest in evaluating the nature of goblet cell carcinoid which has a particularly poor prognosis among carcinoids.
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