Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
Online ISSN : 1882-5133
Print ISSN : 1345-2843
ISSN-L : 1345-2843
A CASE OF ADRENOCORTICAL CARCINOMA AS AN INCIDENTALOMA
Yoshitomo ITOShunji HASEGAWAShigenori HOSHIHideo OHSHIMAShuji KAJIWARAKatsumi SASAKI
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2004 Volume 65 Issue 2 Pages 514-518

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Abstract
A 44-year-old man found to have a giant liver tumor in abdominal ultrasonography and admitted for further examination was suspected of having a right adrenal tumor from CT and angiography. Endocrinological examination showed elevated urine 17-OHCS and 17-KS, so we made a diagnosis of adrenocortical carcinoma and conducted surgical resection. Histopathological diagnosis confirmed adrenocortical carcinoma based on nuclear grade IV, atypical mitosis, 5 or more mitotic figures per 50 high-power fields, etc. Metastases occurred to the liver in months 7, 14, and 31 since surgery. In the first 2 recurrences, tumors were resected but in the third, he underwent embolization for multiple metastases. He is current by under managed medical treatment. The prognosis of adrenocortical carcinoma is very poor because cure is almost impossible without surgical resection. Embolization was effective in this case but is not common for adrenocortical carcinoma. More effective adjuvant therapy or treatment are thus required as an alternative to.
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