Abstract
A case of carcinoma of the ascending colon with metachronous metastasis to the uterus is presented. A 77-year-old woman who had been operated on for ascending colon carcinoma 3 years earlier was referred to the hospital because of a fracture of the iliac bone. Chemical analysis of the blood made for persisting fever and appetite loss revealed elevations of tumor markers (CEA 85.5ng/ml and CA72-4 330u/ml). On magnetic resonance imaging scan of the pelvis, a metastatic tumor in the uterus was suspected. A Hartmann's procedure, a hysterectomy and bilateral oophorectomy were performed. Hystological diagnosis was moderately differentiated adenocarcinoma of the uterus. We conducted CEA staining in both primary and metastatic specimens and gained positive response from them that might be the first attempt in Japan and contribute to prove the relation between the primary and metastatic foci.
The colon carcinoma with metastasis to the uterus is an extremely rare and only six cases including our case, have been reported in the Japanese literature during the past 20 years.
