A 65-year-old man was referred to our department because of dysphagia. Diffusely infiltrating stenosis was detected from the middle thoracic esophagus to esophagogastric junction by an esophagogram and an endoscopic examination. A biopsy specimen indicated mucoepidermoid carcinoma. Systemic CT scan and a scintigram did not visualize aortic invasin and distant metastasis. Retrosternal gastric roll reconstruction followed by a subtotal esophagectomy under a right thoracotomy with lymph node dissection of the three fields was performed. The gross classification of the resected specimen was scirrhous type carcinoma 8cm in longer diameter. Pathologically, the carcinoma was composed of squamous call carcinoma and adenocarcinoma which had a PAS and alcian blue positive mucin. Therefore, the diagnosis of mucoepidermoid carcinoma of the esophagus was made. Histological progress of the lesion was rated pT3N2M0, and comprehensive curability was p A. EM of the surgical margins was less than 1mm. So, postoperative radiotherapy was added to the lower mediastinum; however, 2 months after the operation, multiple hepatic metastasis and metastasis to the fourth cervical verteblae occurred, and the patient died on the 128 postoperative day.