A 69-year-old man was admitted to the hospital for colonic stenosis. With close examination, the stenosis was found to be caused by type II cancer of the sigmoid colon. At the same time, a liver tumor was revealed. Abdominal CT scans revealed a low density mass 3.5cm in diameter in the area of S5 of the liver. CT during arterioportography visualized a wedgeshaped defect at the portion seperated by the portal veins, involving the tumor. CT arteriography visualized an accumulation of a contrast material around the tumor showing a low density mass. No difinitive diagnosis was made. After a sigmoidectomy, a granuloma was revealed by intraoperative echo-guided hepatic biopsy, which predominantly comprised of infiltration of chronic inflammatory cells. The case of inflammatory pseudotumor of the liver associated with malignant tumors should be carefully diagnosed. Therefore, it is important to diagnose by a true-cut biopsy to portions including inside of the tumor and its margin with different echoic levels, under ultrasonographic guidance.