A case of splenic abscess successfully treated with percutaneous drainage is reported. A 78-year-old man was suffered from ileus due to cancer of the sigmoid colon and an artificial stoma was made. After the operation, spike fever was continued and an abdominal CT scan leaded to a diagnosis of splenic abscess. Percutaneous drainage of the splenic abscess brought him a good condition. Percutaneous drainage of splenic abscess has not yet become a common procedure due to a potential risk of bleeding, but it seems to be a safe and effective treatment for the splenic abscess. In future the procedure will be the therapy of choice.