Some patients with adenoid vegetation may manifest. changes in the level of immunoglobulins such as increased immunoglobulin D or decreased γ-globulin.
The present study indicated that adenoidectomy for such subjects with naso-sinusitis helped to correct the abnormal values in immunoglobulins.
It seems that recurrent infections of the nose and paranasal sinuses and the middle ear stimulate the adenoid tissue to produce IgD, causing an increased value of IgD in the circulating blood.
Recurrent infections of the upper respiratory tract particularly of the nose and sinuses should be recognized clinically as a disease which may create immunological disturbances.