Amino acids are indispensable materials for living system at the same time are versatile molecules to be converted to functional materials. Various N-acylamino acids are synthesized from amino acids and their feature properties as amphoteric materials are investigated in terms of structure and function relationship. The evolution of self-organization of amino acid based chiral surfactants from soft assembly to hard mesophase are investigated. As a soft assembly, chiral micelles and lyotropic cholesteric liquid crystals are introduced. And such soft self organized chiral structure was utilized as a template to create chiral mesoporous silica.