Abstract: We experienced a case with a cluster of tumor like polypapilloma in the upper labium in a 6 year 11 month old girl who had generalized dermal hypoplasia and polyanomaly.
Before extracting these tumors, we tried to identify them as benign or malignant using both the common pathologic methods and the molecular biological examination including polymerase chain reaction (PCR). We also examined to identify the human papillomavirus of the specimens from the patient.
The results were as follows:
1. We finally determined these tumors as benign using pathologic method and molecular biological examination.
2. The molecular biological examination is one of the most useful methods for the detection of a small amount of virus, and its procedures are simple and rapid. In this case, we were able to apply this method to clarify the causative virus or micro-organism of the specimens from the patient.
3. In this study, we were not able to identify the type of HPV. These results suggested that the papilloma extracted in this case was a rare type because of being a non general benign HPV type accompanied by manifestation of generalized dermal hypoplasia and polyanomaly.