There are certain diagnostic criteria for diagnosing atopic dermatitis, including Hanifin & Rajka, UK Working Party, and Japanese Dermatological Association criteria. The Japanese Dermatological Association criteria helps in differentiating between multiple diseases presenting with similar signs and symptoms; however, it is difficult for a pediatrician to distinguish between these diseases. Therefore, one should only differentiate the diseases that are exacerbated because of the treatment of atopic dermatitis. If atopic dermatitis is suspected, a pediatrician should frequently observe the skin lesions and confirm the diagnosis. For example, infant eczema and atopic dermatitis do not necessarily have to be distinguished because the treatment for both the conditions is similar. For the assessment of severity of eczema, main assessment scales for healthcare professionals are Severity Index, Investigator Global Assessment, EASI, and SCORAD. EASI and SCORAD assessment scales are not suitable for the assessment of severity of eczema in routine clinical practice as they are time-consuming. However, assessment with EASI is essential before treatment with biologics even by pediatricians. Main assessment scales for patients are POEM and PO-SCORAD. These can also be used at home by patients themselves for understanding the skin condition apart from having to visit clinics.