Recently, multiple malignant tumors in patients with oral cancers have increased. About 10% of patients with oral cancer have multiple primary cancers in other organs. We report on a case in which we conducted radical surgical treatment for multiple primary cancers in advanced stage occurring in the lower gingival and stomach.
An 80-year-old man was referred to our department because of an ulcer of the left lower alveolus. A biopsy showed well-differentiated squamous cell carcinoma. A stomach cancer (poorly-differentiated adenocarcinoma ) was also found by upper gastro-intestinal endoscopy. The stomach cancer was resected by a general surgeon in our hospital. Next, the cancer in the lower gingival was resected after radiation therapy. Histopathologically, the cancer in the lower gingival was pT4N2b and the cancer in the stomach was pT3N0, both diagnosed as being in the advanced stage. There was no evidence of recurrence and metastasis about 2 years after his first visit to our department.