Quality indicators are essential to improve quality of care in the health care setting. Nursing-sensitive indicators (NSIs) consist of direct assessment of actual nursing practice or results strongly influenced by the care provided by nurses. In the critical care setting, it is challenging to develop generally acceptable NSIs because the majority of delivered care is provided by a variety of professionals, and the nursing staff's responsibilities may vary among different ICUs. The development of NSIs in the critical care setting is necessary, in addition to defining what the critical care-specific responsibilities of the nursing staff should be under such settings.