It has been pointed out that before initiating peritoneal dialysis, it is necessary to provide short-term stabilization of the exit site after catheter implantation. For systematic initiation of peritoneal dialysis, we designed a method of peritoneal dialysis initiation, called the Short-term Peritoneal dialysis Induction and Education (SPIED) technique, and examined the effectiveness of this method. The study included twelve patients who started peritoneal dialysis from July 2000 to December 2002. There were nine males and three females. The mean patient age was 61.4±12.7 years. Three patients had diabetic nephropathy and four chronic glomerulonephritis, three nephrosclerosis, and two polycystic kidney. The catheter was not embedded and its tip was exteriorized as usual. The exit-site was draped with a sheet of film and gauze. After surgery, patients stayed at home without dressing the exit-site by themselves. Patients were readmitted to our hospital about ten days later and an education program was started using a critical path. Duration of hospitalization was 2.3±0.8 days for catheter implantation, and 11.5±2.4 days for education. There was no initial complication such as dialysate leak and exit-site infection. During the observation period of 21.6±9.9 months, the incidence of exit-site infection was 1/65.0 patient-months, and that of peritonitis was 1/260.0 patient-months. There were no cases of tunnel infection. We concluded that this method caused little physical and mental stress because there was only one surgery and stabilization of not only the cuff but also the exit-site of catheter was achieved by fixing the exit-site for ten days, leading to a lowered incidence of catheter-related infection.