A cured case of diabetic ketoacidosis, acute renal failure, rhabdomyolysis and pancreatic pseudocyst with MRSA infection is reported. A 36 year-old-male who had a diabetic history was found in a state of delirium after massive alcohol intake and massive sweating. Laboratory findings showed hyperglycemia, ketoacidosis and an elevated serum level of pancreatic enzymes. After treatment using regular insulin and half normal saline, rhabdomyolysis, acute renal failure and thrombophlebitis were observed. After 14 treatments with hemodialysis, rhabdomyolysis, acute renal failure and thrombophlebitis were healed. However infected pancreatic pseudocyst formation associated with acute pancreatitis was observed. Intravenous administration of antibiotics against methicillin-resistant Staphylococcus aureus (MRSA) was not effective. After surgical treatment of external drainage and washing with antiseptics, the infected pancreatic pseudocyst disappeared. A cured case of infected pancreatic pseudocyst with MRSA is exceedingly uncommon. The possible mechanisms of rhabdomyolysis secondary to diabetic ketoacidosis are also discussed.