Wholesale industries have been playing a center role in physical distribution. It is necessary to make deep insight of their behavior to solve a traffic problems in urban area. This paper discusses the historical trend of the wholesale industries and degree of agglomeration of them comparing with production and population by region. It was found that wholesale industry has been shifting their location to demand cities, places of monetary transaction and those of physical distribution have been separating, physical distribution by retail salers is increasing. In addition, multi-levels structure of interregional transaction among wholesalers has analyzed.