The objective of this study is to be clear the influence of the oxidation deterioration of FAME on the property of elastomer, NBR and FKM, by using the soaking test by neat FAME and FAME blend with changing of degree in oxidation deterioration. And the Hansen solubility parameter (HSP) has been applied to the study of the NBR and FKM solubility and swelling by methyl oleate mixed with formic acid, acetic acid, propionic acid, oleic acid, which are formed by oxidation deterioration of FAME. Form the result, NBR increases in mass and volume, and decreases in tensile strength by the oxidized FAME immediately, and FKM also increases in mass and volume by long soaking time.