In the context of multi-material additive manufacturing (MMAM), Cu-based alloys present inherent chemical and physical properties mismatch with other alloys that often lead to cracking, dimensional mismatch and poor bond performance at the interface. This, combined with the lack of optimized laser parameters for the desired arrangement of materials in the 3D-space present a challenge to achieve functionally distinct regions. IN718, which has been used in the past together with Cu-based alloys, benefits from great chemical affinity of Ni with Cu and, and contrary to 316L, has been rarely explored with Cu alloys in PBF-LB/M. The present work focuses on the feasibility study of printing CuCrZr onto IN718 substrate and the influence of PBF-LB/M process parameters on the morphology and the composition of the meltpool. CuCrZr single tracks were printed onto IN718 buildplate for different set of process parameters including laser power, scan speed and layer thickness.