Abstract
Even though Candida is one of the oral flora, the prevalence in healthy young subjects without oral disorder has not completed yet. Based on this situation, the aim of this study was to examine the oral carriage of Candida in the host without any systemic disorders and to reveal predisposing factors associated with virulence of Candida in young adults. Samples were collected from oral cavity in 108 students attending the School of Life Dentistry at Niigata, The Nippon Dental University. Average age of subjectives was 23.5 years old and 81 males and 27 females in gender. Before examination, questionairs were corrected concerning to daily mediation or complication of systemic disorders to exclude from healthy groups. Yeasts were isolated according to CHROMagar method and identified using a combination of the API 32C AUX yeast system. Result of 33 examined from 108 subjectives were Candida positive and positive rate was 30.6% respectively. Thirty-three identified species were all Candida albicans and 1 Candida glabrata was simultaneously identified from the same sample judged by mean of CHROMagar. Different host factors were analyzed statistically to establish their importance as predisposing factors to allow Candida colonization. However, relationship between isolation rate of Candida and loss of salivary flow rates was remarked. These results suggest that oral yeast status may be influenced by salivary flow rates.