The purpose of this study is to investigate the behavior of a transient powder-laden liquid jet coaxially injected into a pipe flow. The visualization techniques adopted include a high-speed camera and computational fluid dynamics. The equivalent diameter and density of the adopted powder are 700nm and 2700kg/m³, respectively. The computation also simulates the present target flow against the experiment, based on the one-way coupling for the particle movement. As a result, the spreading angle and centerline velocity of the transient particle-laden jet are given between the experiment and computation.