Thermodynamic consideration of impurity removal from molten iron was conducted. Possibility and extent of impurity oxidation and evaporation was discussed. As a first step, vapor pressure of pure impurity and equilibrium oxygen partial pressure that pure impurity coexist with its oxide were calculated at steelmaking temperature for 48 elements. The results were categorized by groups in the periodic tables and the possibilities of impurity removal for each element were estimated. In the next step, more accurate estimation was conducted using the thermodynamic information of impurities in molten iron for 24 elements. The estimation could not be done for the elements that thermodynamic information in molten iron was unavailable. Estimation for the removal of some elements differed due to the effect of considering the activity coefficient in molten iron. It was made clear the removal possibility can be roughly estimated by thermodynamic consideration of pure elements. However, the thermodynamic information in molten iron is required for precise estimation.