Acute cholecystitis is a common disease, but hemorrhage of the gallbladder is a rare complication. We report a case of hemorrhage of the gallbladder with intraperitoneal bleeding. A 48-year-old man had been treated for alcoholic liver cirrhosis and chronic renal failure and had been undergoing hemodialysis. He visited a doctor for right upper abdominal pain and was diagnosed with acute cholecystitis. As conservative therapy was not effective and intraperitoneal bleeding was detected, he was shifted moved to our hospital. He underwent an emergency operation for suspected gangrenous cholecystitis. The gallbladder was enlarged and filled with fresh blood, and there was hemorrhage from the gallbladder wall, although there was no perforation. Cholecystectomy was performed. He was discharged on postoperative day 10. Hemorrhage of the gallbladder shoul be considered in the differential diagnosis of acute cholecystitis in which there are underlying disease complications, as in our case.