We report two patients with intractable postoperative chylous ascites that was successfully treated with octreotide. The first case was a 49-year-old male who underwent pancreaticoduodenectomy. Fasting temporarily improved his ascites, however, the patient deteriorated with oral intake. Furthermore, insufficient drainage of ascitic fluid led to abdominal bloating. The subcutaneous administration of octreotide (200μg/day, twice daily) decreased the amount of fluid that was drained and relieved the abdominal bloating ; the drainage tube was removed 20 days after the start of octreotide treatment. The second patient was a 77-year-old female who had a resection of a perforated transverse colon cancer. A minimum of 1,000mL/day of chylous ascitic, fluid was produced when the patient was tube fed. The chyle disappeared and the amount of fluid that was drained dramatically decreased the day after subcutaneous administration of octreotide (200μg/day, twice daily) was started. The drainage tube was removed 12 days after the start of octreotide treatment. Octreotide appears to be an effective treatment for intractable chylous ascites.