In the present study, uniform survey for commercially available RIA kits of AFP was performed. RIA kits surveyed were AFP RIA kit (RIABEAD), AFP RIA kit, RIAGNOST AFP (Tachisorb), AFP "Eiken"and SPAC AFP. Coefficient of variations (±2SD) of measured values by these five kits are 7.4〜9.3%, 5.2〜11.1%, 7.0〜13.4%, 5.5〜10.7% and 4.9〜7.2%, respectively. C.V. values were smaller in solid state RIA kits than in liquid phase RIA kits. Mean of measured values by SPAC kit was significantly higher than those by the other kits (p<0.005). The analysis of the standard curves of five RIA kits revealed that the best fitting statistical standard curve was different for each RIA kits. Thus it was sugested that the best fitting statistical standard curve should be selected for each RIA when computer analysis was used for the calculation of measured value.