Mandibular reconstruction in patients with lost mandibular continuity due to segmental resection is essential for both functional and aesthetic recovery. One reconstruction method involves the use of a titanium mesh plate and autogenous bone grafting. Mandibular reconstruction using this method has several advantages, including procedural simplicity and shorter operative time. Additionally, this method allows the reconstruction of a shape close to the anatomical contour of the mandible, making prosthetic treatment easier. However, there are few reports on the long-term outcomes of cases in which occlusal loading was achieved after reconstruction.
In this study, we conducted a clinical evaluation of long-term cases in which mandibular reconstruction was performed using titanium mesh and autogenous iliac bone grafting, followed by implant-supported prosthetic treatment. The results showed that in cases of benign tumors, no complications related to the titanium mesh occurred during the long-term follow-up （mean duration of 16 years and 8 months）. However, in 40％ of cases involving malignant tumors, removal of the titanium mesh was necessary.
When using titanium mesh in malignant tumor cases, it is recommended to either remove the titanium mesh after bone regeneration or ensure adequate soft tissue reconstruction during initial surgery.