One hundred ninety-two cases with hypopharyngeal carcinoma who underwent pharyngo-laryngo-esophagectomy at Kurume University Hospital between 1989 and 2011 were clinically analyzed. The 192 cases consisted of 173 males and 19 females with ages ranging from 39 to 84 years old (median: 63). The five-year overall survival rate and disease-specific survival rate were 45% and 60%, respectively. Ninety-five patients were alive, thirty-one patients died because of distant metastasis, and thirty patients died because of other diseases, twenty-one patients died because of lymph node metastasis, 9 patients died because of primary cancer and 6 patients died because of postoperative complications. In cases with operative complications, 29 patients showed anastomotic stricture, 5 patients showed anastomotic fistula, 4 patients showed total necrosis of the transplanted jejunum, 4 patients showed infection around the tracheostoma. This review indicates that the treatment result of hypopharyngeal carcinoma has dramatically improved because of well-organized team practice.