Encapsulating peritoneal sclerosis （EPS） is the syndrome that causes intestinal adhesion and inflammatory capsules due to multiple surgical history or peritoneal dialysis, etc. and results in recurrent small bowel obstruction. In our experience, three of 22 cases undergone the small bowel anastomosis for two years were complicated by the postoperative leakage. All of them were EPS patients. One case was caused by anastomotic disruption, another was caused by intestinal injury during adhesiolysis, and the other was caused by the both of them. All leakages were treated with conservative therapy with drainage. In EPS patients, it is reported that they have high risk of anastomotic disruption and intestinal injury after small bowel anastomosis. Therefore, it is important to minimize adhesiolysis and intestinal resection. When the leakage occur, the drainage is effective for the treatment. In EPS patients surgeons should place some drainage tubes after small bowel anastomosis considering about the leakage.