Critical path for visit frequency and content during the early period at home were developed. For the purposes of delivering efficient and high quality nursing care during home visits to persons newly started on home oxygen therapy (HOT) at early period. The HOT path provided for four visits at seven to thirty day intervals for two months. For this study, evaluating outcomes for clients and the cost effectiveness ratios for services at total of 20 clients were randomly assigned to 10 clients for HOT path and control groups, and analyzed except one client for HOT path group due to readmission. Three measures were developed for this study. Outcome attainment ratios calculated for 14 care concerns were one measure of service effects. A second measure of effect was goal attainment with regard to five transcending client or nursing concerns. To calculate nursing service costs for each client's hours of direct care and management and coordination related to the client were multiplied by the hourly cost of nursing service. Results: 1) Outcome attainment ratios were higher for the HOT path group, and significantly higher for the care concerns of disease management, physiotherapy, self-care, excretion, and cleanliness; 2) Goal attainment was significantly higher for the HOT path group for "home oxygen therapy can be safely carried out", and "resuming daily life before the home oxygen therapy started; 3) The cost-effectiveness ratios were higher for the HOT path group, outcome attainment ratios and goal attainment were significantly higher in comparison to the control group. These results suggest the overall effectiveness of the HOT path, but we need to examine additional clients to solidify our results.