1993 Volume 18 Issue 2 Pages 120-125
This paper describes our experience in general anesthesia for a patient with 3p trisomy. 3p trisomy is caused by a chromosomal aberration due to the partial trisomy of the short arm of chromosome 3. The patient, a 9-year-old girl weighing 25kg, was scheduled for dental treatment under general anesthesia. She had the characteristic face of 3p trisomy and complications of mental retardation, muscle weakness, and PDA (post-operative). After premedication with atroplne (0.25㎎), anesthesia was induced with thiamylal (150㎎) and vecuronium bromide (2.5㎎) and maintained with sevoflurane in nitrous oxide and oxygen. Mask ventilation, laryngoscopy and intubation were easy. No remarkable changes were observed in the circulatory and respiratory systems. The duration of anesthesia was 3 hrs. On the basis of this experience, problems in the anesthetic management of 3p trisomy syndrome are discussed.