The large-scale aggregation of fast demand response (DR) from hundreds or thousands of building multi-type air-conditioners, i.e., variable refrigerant flow (VRF) air-conditioners, is anticipated to serve as a flexibility resource for balancing supply and demand in future smart grids. This paper proposes a dynamic equilibrium DR aggregation method, inspired by birth-death regulating balance of billions of cells in biological systems. We developed a virtual model of an office building block comprising 50 buildings and 660 multi-type air-conditioners. Using the model, we conducted digital simulations and found that the proposed dynamic equilibrium method exhibits better power reduction precision than the conventional set-temperature shift and group-rotation methods.