A wide range of systems and techniques has been developed in order to satisfy the requirement of ventilation for residential buildings. However, there is still no clear and precise information for architects and engineers to determine the performance of the various ventilation systems and their availability of application. In this research, some new evaluation indices to highlight the occupant exposure to indoor air pollutants were introduced, and then numerical simulations were carried out by COMIS simulation Model to evaluate the performance of various ventilation systems. In addition, the influence of various factors and the relationship between indexes are discussed.