The present paper discusses the effects of factors on psychological responses where a personal air-conditioning system with non-isothermal fluctuating airflow was applied, and design method of task air-conditioning system from the viewpoints of energy saving and thermal comfort. The effects of factors on psychological responses were examined by many experiments in a simulated office room. The nominal supply air velocity, supply air temperature differential, and vane-swing period of the personal unit were considered as factors with sex of subjects. Voting were conducted as thermal comfort and evaluation on surrounding environment. The nominal supply air velocity range of 1.0〜1.5m/s, supply air temperature difference of 5℃, vane-swing period of free between 10s and 30s, were also proposed for maintaining moderate thermal comfort.